Noncommunicable diseases (NCDs), such as heart disease, cancer, chronic respiratory disease, and diabetes, are the leading cause of death worldwide and represent an emerging global health threat. Deaths from NCDs now exceed all communicable disease deaths combined. NCDs kill 41 million people each year, equivalent to over 7 out of 10 deaths worldwide. Changing social, economic, and structural factors such as more people moving to cities and the spread of unhealthy lifestyles have fueled the NCD crisis that kills 15 million people prematurely—before the age of 70—each year. The high burden of NCDs among working age people leads to high healthcare costs, limited ability to work, and financial insecurity.
Evidence shows that NCDs and their risk factors increase the likelihood of hospitalization or death from COVID-19 across all age groups, a stark reminder of the role of NCDs in outbreak preparedness and response. NCDs can affect vulnerability to illness, pathogen performance, and the ability of health systems to handle health threats. High rates of NCDs perpetuate poverty, strain economic development, and burden fragile health systems, making countries less resilient when emergencies like infectious disease outbreaks or natural disasters occur. Integrating noncommunicable diseases in global health security approaches is important to addressing emergencies and ongoing health needs, increasing health equity, and building trust among partners.
Addressing NCDs enhances global economic and health security and supports progress towards the United Nations’ Sustainable Development Goals. Countries with healthier populations are more stable and prosperous, more viable trading partners, better able to avoid health crises and outbreaks, thus affecting U.S. national interests.

